我想成为医药行业的销售代表。我选择的公司是强生医疗器械公司。强生公司成立于1886年，是一家美国跨国医疗器械、药品和消费品包装制造商。它的普通股是道琼斯工业平均指数（dowjonesindustrialaverage）的一个组成部分，该公司是《财富》500强之一。强生公司在2005年之前连续七年在哈里斯互动公司的全国企业声誉调查中名列榜首，[2]2008年被《巴伦杂志》评为世界上最受尊敬的公司，[3]2005年被美国国务院授予本杰明·富兰克林公共外交奖的第一家公司为国际教育项目提供资金。
在这本杂志中，作者提到，医生们想知道是否有一种更简单、侵入性更小的方法来评估有睡眠问题的患者，他们现在必须在医院或诊所呆上一晚，戴着几十个连接到昂贵电子设备的电极。美国每年进行100多万项睡眠研究，以检测慢性睡眠障碍。目前，这些要求患者在一家诊所过夜，诊所连接多达30个传感器，从脑电波电极到血氧追踪器。这些研究的数据被分为时间段，并在一个昂贵的过程中被人工分类为各种睡眠状态。对此，一组学生想出了一件“睡眠感应衬衫”，病人可以在家里、自己的床上穿。这件衬衫可以记录足够的关于呼吸模式的数据，以提供标准方法的成本和不便的一小部分答案。
在清醒、睡眠和活动状态下对心肺参数进行动态监测可以扩大我们对健康和疾病的了解。传感衬衫由一件集成了生理监测传感器的T恤、一个数据采集单元（大曲）和一套基于PC的软件组成。一些生命体征，如心电图（ECG）、胸腔（RC）和腹部（AB）呼吸。光容积图（PPG）。SpO2和姿势/活动可通过衬衫获得。生理数据存储在microSD存储卡中，离线分析提取心率（HR）、呼吸频率、血氧饱和度、潮气量（TV）、脉搏波传导时间（pwt）、呼吸窦性心律失常（RSA）等参数。在传感衬衫系统中，心电信号是通过有源电极采集的。PPG和ECG由一个高速16位模数转换器以500hz采样，用于精确的pwt计算。在呼吸感应容积描记和PPG电路中，均采用脉冲幅度调制技术进行信号调理，以降低功耗。整个系统由2节1600毫安时AA电池供电，可连续工作48小时以上，不间断。基本性能测试表明，该系统能够有效地采集ECU-RC和AB呼吸信号，PPG信号，提取HR等参数。呼吸频率。SpO2和电视信号。这种先进的动态监测系统可用于家庭保健和科学研究。这一概念目前正在进行广泛的测试，由一家总部位于波士顿的名为Rest Devices的公司进行商业化，这家公司是前学生和他们的医学导师建立的。
Literature review代写:医药行业强生医疗器械睡眠研究
I would like to be a GO Sales Representative in the Pharmaceutical industry. The company I choose is Johnson & Johnson Medical Devices. Johnson & Johnson is a U.S multinational medical devices, pharmaceutical and consumer packaged goods manufacturer founded in 1886. Its common stock is a component of the Dow Jones Industrial Average and the company is listed among the Fortune 500. Johnson & Johnson ranked at the top of Harris Interactive's National Corporate Reputation Survey for seven consecutive years up to 2005,[2] was ranked as the world's most respected company by Barron's Magazine in 2008,[3]and was the first corporation awarded the Benjamin Franklin Award for Public Diplomacy by the U.S. State Department in 2005 for its funding of international education programs.
In this journal, the author mentioned that Doctors wondered if there might be a simpler and less-invasive way of assessing patients with sleep problems, who must now spend a night in a hospital or clinic wearing dozens of electrodes connected to expensive electronic equipment. Over 1 million sleep studies are performed annually in the US to detect chronic sleep disorders. Currently these require a patient to spend a night in a clinic connected to up to 30 sensors, ranging from brain wave electrodes to blood oxygen trackers. Data from these studies are divided into time segments and which are manually categorized into various sleep states in a costly process. In response, a team of students came up with a “sleep sensing shirt” that patients could wear at home, in their own beds. The shirt could record enough data about breathing patterns to provide answers at a fraction of the cost — and inconvenience — of the standard approach.
Ambulatory monitoring of cardiopulmonary parameters during wake, sleep, and activity states can expand our understanding of health and diseases. The Sensing Shirt Consists of a T-shirt with sensors integrated for physiological monitoring, a data acquisition unit (DAQU), and a set of PC-based software. A number of vital signs such as electrocardiogram (ECG), rib cage (RC) and abdominal (AB) respiration. photoplethysmogram (PPG). SpO2, and posture/activities can be acquired by the shirt. The physiological data are stored in a microSD memory card, and then analyzed offline to extract parameters such as heart rate (HR), breathing rate, SpO2, tidal volume (TV), pulse wave transit time (PWTT), and respiratory sinus arrhythmia (RSA). In the Sensing Shirt system, the ECG is acquired by means of active electrodes. PPG and ECG are sampled by one high-speed 16-bit, analog-to-digital converter at 500 Hz for precise PWTT calculation. Technique of pulse amplitude modulation is used for signal conditioning both in respiratory inductive plethysmography and PPG circuits to reduce the power consumption. Powered by 2 AA batteries with 1600 mAh capacity, the whole system can work more than 48 h continuously without interruption. Basic performance tests demonstrate that prototypes of this system can capture ECU RC and AB respiration, and PPG signals effectively, and extract parameters such as HR. breathing rate. SpO2, and TV accurately. This advanced ambulatory monitoring system may be used in both home healthcare and scientific research. That concept is now undergoing extensive testing, on its way to commercialization by a Boston-based company, called Rest Devices, that former students and their medical mentor have set up.
Literature review代写:医药行业强生医疗器械睡眠研究
